Practice Guidelines Developed or Endorsed by C17
*page and guidelines are archived and not updated*
Antifungal Prophylaxis:
- C17 guideline for primary antifungal prophylaxis for pediatric patients with cancer or hematopoietic stem cell Transplant Recipients (Completed; February 2014)
Full Guideline (English Version)
- A condensed version has been published in Pediatric Blood and Cancer (2014) 61:393-400
- Endorsed by ASPHO, COG and POGO
Antithrombotic Therapy and Prevention of Thrombosis:
- Antithrombotic Therapy in Neonates and Children: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-based Clinical Practice Guideline has been endorsed by C17.
- The guideline is available here.
Chemotherapy-induced Nausea and Vomiting (CINV):
- The following Pediatric Oncology Group of Ontario (POGO) guidelines related to the management of CINV have been endorsed by C17:
- Guideline for the classification of the acute emetogenic potential of antineoplastic medication in pediatric cancer patients (2010)
- Guideline for the prevention of acute nausea and vomiting due to antineoplastic medication in pediatric cancer patients (2012)
- Guideline for the prevention and treatment of anticipatory nausea and vomiting due to chemotherapy in pediatric cancer patients (2014)
- Full versions of the POGO CINV guidelines and information regarding related journal publications are available here.
Fever and Neutropenia:
- The international guideline for the management of fever and neutropenia in children with cancer and/or undergoing hematopoietic stem cell transplantation (2012) has been endorsed by C17
- The complete guideline, a condensed version (published in the Journal of Clinical Oncology) and supporting materials are available from The Hospital for Sick Children.
Platelet Transfusion Thresholds:
- C17 guideline for platelet transfusion thresholds for pediatric hematology/oncology patients (Updated March 2011) This guideline has been endorsed by the Pediatric Oncology Group of Ontario





